I like the blue Mohawk

I'm not sure if you mean dose 2 or the second phase of chemo. It sounds like dose 2 .... A common regimen for breast cancer is AC+T (Adriamycin and Cytoxan together for X treatments, followed by Y treatments with Taxotere or Taxol).
I think it was the Adriamycin (aka "the red drug") that was the worst.
FWIW, the Taxanes (Taxol or Taxotere) won't be nearly as bad, if that's what she will get next. Denice has had both. A survivor/volunteer at the cancer center did emphasize (from personal experience) what the nurse had already told her - it's very important to keep the arm still while the Taxotere is running. She listened to his advice, and didn't have much trouble with it.
Also, it takes several treatments for the nurses to dial in the right combination of preventative nausea drugs for each patient. They probably can't prevent it altogether, but they can probably reduce the severity and duration.
In other words, while I don't know what regimen your wife is on,
the hardest part is probably at the beginning. I won't say it gets easy, but it gets easier.